Acetamide, 2-cyano-2-[[[(9H-fluoren-9-ylmethoxy)carbonyl]oxy]imino]- - Names and Identifiers
Acetamide, 2-cyano-2-[[[(9H-fluoren-9-ylmethoxy)carbonyl]oxy]imino]- - Physico-chemical Properties
Molecular Formula | C18H13N3O4
|
Molar Mass | 335.31 |
Density | 1.38±0.1 g/cm3(Predicted) |
Boling Point | 524.6±43.0 °C(Predicted) |
pKa | 11.14±0.50(Predicted) |
Acetamide, 2-cyano-2-[[[(9H-fluoren-9-ylmethoxy)carbonyl]oxy]imino]- - Introduction
Nature:
N-(((9H-fluoren-9-yl)methoxy)carbonyloxy)-2-amino-2-oxoacetimidoyl cyanide is a solid, white crystalline powder at room temperature. It has low solubility in water and good solubility in organic solvents (such as dimethyl sulfoxide, dichloromethane, methanol, etc.).
Use:
N-(((9H-fluoren-9-yl)methoxy)carbonyloxy)-2-amino-2-oxoacetimidoyl cyanide is mainly used as a protecting group reagent in chemical synthesis, and it can react with amino compounds to generate N-protecting group products. Commonly used in peptide synthesis and solid phase synthesis and other fields of organic synthesis. In addition, it can also be used as a precursor for biologically active compounds.
Preparation Method:
The preparation of N-(((9H-fluoren-9-yl)methoxy)carbonyloxy)-2-amino-2-oxoacetimidoyl cyanide is generally accomplished by chemical synthetic methods. Specific steps may include reacting fluorene anhydride with methanol to produce fluorene methoxy formate, and then reacting with benzyl formate to obtain benzyl fluorene methoxy formate. Finally, the product was reacted with a hydroammoniated dehydrating agent to produce N-(((9H-fluoren-9-yl)methoxy)carbonyloxy)-2-amino-2-oxoacetimidoyl cyanide.
Safety Information:
Safety information about N-(((9H-fluoren-9-yl)methoxy)carbonyloxy)-2-amino-2-oxoacetimidoyl cyanide should be stored in a dry, cool place away from direct sunlight. Care should be taken to avoid inhalation, ingestion or contact with skin during use. Wear appropriate personal protective equipment, such as lab gloves and safety glasses. If it comes into contact with skin or eyes, rinse immediately with plenty of water. In all cases, the use of chemicals should follow safe handling and handling procedures and comply with relevant safety regulations.
Last Update:2024-04-09 21:54:55